Biochemistry
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Thursday, January 29 2009
By Denis Vignes on Thursday, January 29 2009, 16:15
- Review of protocols / raw data / reports
- Critical phase inspections
- Monitoring and maintenance of archives for material and study documentation
- Internal quality assurance program
- ISO14001 certification (Environmental Management System)
By Denis Vignes on Thursday, January 29 2009, 16:12
- Gel permeation chromatography (GPC)
- Automated biochemistry analyzer (Pentra 400, Horiba ABX)
- HPLC systems with UV detection equipped with enzyme delivery pumps for lipoprotein assay (on-line detection of cholesterol, triglycerides, phospholipids or ApoA1)
- HPLC systems with fluorescence detection
- Micro-plate reader (96 wells) for colorimetric assays
- Ultracentrifugation (in partnership)
- Apparatus for 1-D vertical electrophoresis (MiniProtean® Tetra Cell, BioRad)
- Storage at –20°C and –80°C (monitored freezers)
By Denis Vignes on Thursday, January 29 2009, 16:04
Biomarkers and Endogenous compounds expertise
- Development, validation, transfer of analytical methods and analytical assays for the analysis of macromolecules:
- C-reactive protein (CRP)
- Insulin
- Bilirubin
- ApoA1
- Cytokines
- Vitamins
- Synthetic proteins, etc.
- Working in the fields of pre-clinical (laboratory species) and clinical studies
- Wide range of species and matrices (blood, plasma, serum, bile, urine, skin strippings, etc.)
- Multiple biochemistry parameter screen (currently more than 50 parameters, up to 15 per sample) on low sample volumes (80 µL)
- Single immunoassays (ELISA), multiplex immunoassays (Luminex® technology, in partnership), colorimetric assays (µBCA, Biuret)
- Lipoprotein profiles (HDL/LDL/VLDL) by size exclusion chromatography (SEC) with on-line enzymatic detection (single or dual) for:
- Cholesterol
- Triglycerides
- Phospholipids
Please contact us to ask about analyses of other biomarkers or endogenous compounds.
